MOLECULAR INTERPLAY OF PRO-INFLAMMATORY TRANSCRIPTION FACTORS AND NON-CODING RNAS IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA

Molecular interplay of pro-inflammatory transcription factors and non-coding RNAs in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma is the sixth most common cancer in the developing world.The aggressive nature of esophageal squamous cell carcinoma, its tendency for relapse, and the poor survival prospects of patients diagnosed at advanced stages, represent a pressing need for the development of new therapies for this disease.Chronic inflammati

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Learning Needs of Pharmacists for an Evolving Scope of Practice

Around the world, changes in scope of practice regulations for pharmacists have been used as a tool to advance practice and promote change.Regulatory change does not automatically trigger practice change; the extent and speed of uptake of new roles and responsibilities has been slower than anticipated.A recent study identified 9 pre-requisites to p

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One-Tube-Only Standardized Site-Directed Mutagenesis: An Alternative Approach to Generate Amino Acid Substitution Collections.

Site-directed mutagenesis (SDM) is a powerful tool to create defined collections of protein variants for experimental and clinical purposes, but effectiveness is compromised when a large number of mutations is required.We present here a one-tube-only Kids Backpack standardized SDM approach that generates comprehensive collections of amino acid subs

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